YES! You can you reverse your T-Score… Normal… Osteopenia… Osteoporosi – Supplements

I went down the Algae Cal rabbit hole and googled strontium. Btw, their website and marketing is OUTSTANDING! I guess not outstanding enough, because I didn’t buy it

Something I saw said it might not be good for those with heart disease, so I stopped looking. I’m not saying that was accurate info, I never checked.

Thanks so much for sharing this! Indeed the bouncing (medicine ball) sounds like a lot more fun. Hope this is going to work for you – I would love to read an update indeed. I’m preparing for a move – and have collected too many things , but this is definitely on my ‘watch’ list.

My wife used 8mg rapamycin a week for 12 weeks and off 4 weeks . Does everything but taurine . What is your Rapamycin schedule and dose?

So if I understand you are doing the rapamycin and this taurine every day. I too am dealing with bone loss and started taking this Rapamycin to stop the loss. I would love to know how much are you taking of both? I am reading about 6 grams on the taurine? I am currently taking Rapacan 2 mg every week and slowly moving up my dosage. I have had to take breaks to give my body time off since it has had a harder time with side effects but fell I am in a good spot now.

Yes… as a 185 pound 6ft tall toned body male… I take 6 mg rapamycin/zydus once a week.

I take about 6 grams… one full teaspoon of taurine in my coffee… every morning with a teaspoon of creatine.

At night I take K2 vitamin and a calcium supplement.

No doubt this reversed my DEXA bone density score in one year from osteopenia -1.2 to normal at -.8

I believe that low bone density is not necessarily the main cause of increased fracture rate. Poor balance and brittle bone is probably a bigger factor.

I’ve been taking Taurine subcutaneously – haven’t taken any specific tests to show the impact but based on all of the positive studies, I will keep taking it.

Reminded me of this MR preprint:

Moreover, mTOR inhibition significantly reduced body mass index (BMI), basal metabolic rate (BMR), height, and age at menopause, while increasing bone mineral density.

So far as I can tell, the basic cause of osteoporosis is that osteoblasts don’t do their job well. This may be a general problem with stem cells losing function.

Rapa (sayth google) can affect osteoblasts. Hopefully, the effect is more positive than not …

Rapamycin, a small molecular inhibitor of the mammalian target of rapamycin (mTOR), can affect osteoblasts in a number of ways, including:

• Preserving osteoblast viability: Rapamycin can reduce apoptosis and preserve osteoblast viability in the presence of lipotoxic concentrations of palmitate ¶.
• Inducing osteoblastic differentiation: Rapamycin can induce osteoblastic differentiation in human embryonic stem cells (hESCs) by stimulating the BMP/Smad pathway.
• Promoting autophagy: Rapamycin can induce autophagy, which can protect osteoblasts.
• Inhibiting osteoblast proliferation and differentiation: Rapamycin can inhibit osteoblast proliferation and differentiation in MC3T3-E1 preosteoblastic cells and primary mouse bone marrow stromal cells.
• Impairing bone accrual: Rapamycin can impair bone accrual in young adult mice.

https://www.google.com/search?q=osteoblast+rapamycin&sca_esv=ecab62f8c07129e5&rlz=1C5CHFA_enUS830US830&sxsrf=ADLYWIKrnuQiM4IuLMG7NoreocJMJxWA1Q%3A1736101117702&ei=_cx6Z9bHKpLP0PEP_O-k2QY&ved=0ahUKEwiWuqjTmN-KAxWSJzQIHfw3KWsQ4dUDCBA&uact=5&oq=osteoblast+rapamycin&gs_lp=Egxnd3Mtd2l6LXNlcnAiFG9zdGVvYmxhc3QgcmFwYW15Y2luMggQIRigARjDBDIIECEYoAEYwwQyCBAhGKABGMMEMggQIRigARjDBEitGlAAWMYRcAB4AJABAJgBUKAB4wSqAQIxMLgBA8gBAPgBAZgCCqAC-ATCAgYQABgHGB7CAgcQABiABBgNwgIIEAAYBxgIGB7CAgsQABiABBiGAxiKBcICChAhGKABGMMEGAqYAwCSBwIxMKAH9DM&sclient=gws-wiz-serp

Beth my score at 60 was spine -2.5 and the other 2 places -1.9. I had not had a DEXA until I broke femur 7 years later and was so pleased that it was the same. Still not good but expected much worse due to my fatigue/lack of exercise. I think it had to be the HRT that kept it stable. Have one scheduled for May which will be another 4 years. I do take calcium, K, D, creatine, and recently added a collagen powder that algae cal makes. I will now add taurine, but think HRT has worked the best for me. If only I’d started it at 50 but nobody told me I should and even now a lot of docs don’t like it.

Yep, what I read says that HRT is good, up to about age 60. I gather they think it shouldn’t be started after 60, but is ok to continue if it has been started, depending on the person.

It helps, but I’m still hoping for an actual cure, that is, kickstarting the osteoblasts into action again, something that will work at any age & gender.

FWIW, lifespan.io is featuring an article on helping out MSC’s, so far in mice, but they thing they have results to explore more: Keeping Stem Cells Healthy and Young | Lifespan.io

Hi Elizabeth I’ve heard that re if you haven’t taken before 60, or 10 years after menopause, but it’s controversial. Some docs now say can take anytime. I have a friend just started pellets at 79 and is feeling great much better sleep more energy etc. I feel the same on or off just take for bones. At 60 was given estrone which I’ve recently read won’t help bones as it’s such a weak estrogen but it had to be what helped mine. I asked to have a level drawn after 7 years and the doc didn’t think necessary as “it’s a standard dose.” It was actually a lesser dose than that. I persisted and estrogen was 557! There again some docs said ok one NP said get off immediately. So many opinions out there. I’m now on an estradiol patch but it has no testosterone. Another thing I take forgot to mention is stronium so maybe it’s been helping too.

Wait, mTOR inhibition makes women hit menopause earlier in life? That doesn’t make any sense. What am I missing?

That has to be a typo, an unfortunate one.